The US Food and Drug Administration (FDA) banned the use of the dye Red Dye 3 in food and ingestible drug products earlier this week.

Red dye No. 3 is officially banned in the United States. The announcement has raised concerns about the safety of other food dyes, like red dye No. 40.

For decades, FD&C Red No. 3 has added its vivid cherry-red hue to candies and cupcakes—but its risks have been debated just as long.