Finally, “The Substance” is very much a woman’s movie. The way writer-director Coralie Fargeat presents Demi Moore and Margaret Qualley — the matter-of-fact way in which she films their bodies, and the trust that she elicits from them — has the unmistakable stamp of a woman director. This is obvious within minutes.

From daunting high-energy choreography to nine-hour prosthetic application, the stars tell EW "The Substance" was a satisfyingly grueling, months-long shoot.

Demi Moore, Margaret Qualley, Dennis Quaid and more stars hit the red carpet for the L.A. premiere of their film, 'The Substance.' See all the photos.