Cytochrome P450 (P450) enzymes are important in the metabolism of steroids, vitamins, carcinogens, drugs and other compounds. Two of the commonly used assays in this field are the measurements of ...

Cytochrome P450 enzymes metabolize drugs and contribute to harmful drug-drug interactions. To decipher p450 activities, Veith et al. screen ∼17,000 compounds, including >1,000 FDA-approved drugs ...

The cytochrome P450 (CYP) enzymes are a protein superfamily involved in the synthesis and metabolism of drugs, toxins and normal cellular components.

Cytochrome P450 (CYP450), is a family of hemoglobin-coupled monooxygenases. In mammals, CYP450 oxidizes steroids, fatty acids, and xenobiotics, playing an important role in the metabolism of various ...

His “Cytochrome P450 Homepage” provides pages upon pages of P450 information for a number of species, along with phylogenetic trees, 3-D structures, nomenclature resources, ...

Tissue-preferential recruitment of electron transfer chains for cytochrome P450-catalyzed phenolic biosynthesis. Science Advances , 2023; 9 (2) DOI: 10.1126/sciadv.ade4389 Cite This Page : ...

Cytochrome P450 CYP3A4/5 Expression as a Biomarker of Outcome in Osteosarcoma. Hassan R. Dhaini, Dafydd G. Thomas, Thomas J. Giordano, Timothy D. Johnson, J. Sybil Biermann, Kirsten Leu, Paul F.

Trenk, D, Hochholzer, W, Fromm, MF, et al. Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective ...

Previous studies have suggested that austocystin D is oxidized by cytochrome P450 (CYP) oxygenases which then induces DNA damage and suppresses cell proliferation. In this study, we showed that ...