Actin, microtubules, intermediate filaments and septins are four major components of the cytoskeleton. They all have crucial roles in cell-autonomous immunity. There is currently intense investigation ...

The cytoplasm of eukaryotic cells contains an elaborate filamentous protein meshwork — the cytoskeleton — which comprises three distinct but integrated fibrous polymers: filamentous actin (F-actin; ...

The actin cytoskeleton is a dynamic network made up of actin polymers and associated actin binding proteins. The actin cytoskeleton was originally isolated as a component of the actomyosin complex in ...

The rearrangement of the cell´s inner scaffold, the cytoskeleton, is a vital process for immune cells. In a new collaborative study, a rare inherited disease revealed a hitherto unknown role of a ...

Researchers from Cleveland Clinic's Florida Research and Innovation Center (FRIC) found that disruption of a cellular structure, known as the actin cytoskeleton, is a "priming signal" for the body to ...

Why do some children develop a brain that is too small (microcephaly)? An international research team involving the German Primate Center—Leibniz Institute for Primate Research (DPZ), Hannover Medical ...

Researchers from Freiburg and Kiel discovered that actin acts in the cell nucleus and is partly responsible for the expression of male sexual characteristics Steroid hormones, to which belong sex ...

SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When researchers discovered that SETD2 is mutated ...

Researchers have developed a highly sensitive technique to quantitatively evaluate the extent of cytoskeleton bundling from microscopic images. Until now, analysis of cytoskeleton organization was ...

Cells are characterized to be stable yet highly flexible. They constantly modify their shape and even move through tissue. These vital properties are based on a dynamically organized network of ...

Prof. Michael Murrell's group (lead author Zachary Gao Sun, graduate student in physics) in collaboration with Prof. Garegin Papoian's group from the University of Maryland at College Park has found ...

Most cell structures are not visible to the naked eye without using stains for visualization. The stains used in these images highlight how cell biologists use tricks to “see the invisible.” Invite ...