Similarly, estrogen elevates skin's levels of hyaluronic acid, improving barrier function, protecting cells against oxidative ...

Their experiments showed that ERα could bind to DNA without estrogen but did so less precisely and less stably. When estrogen was present, ERα molecules dimerized more efficiently and exhibited ...

Researchers uncovered how estrogen heightens gut sensitivity in females by activating PYY-secreting L-cells, which stimulate ...

A percentage of cells out of 100 that have hormone receptors. A score of 0% means no cells have receptors. 100% means all cells have them. An "Allred score" between 0 and 8.

A new Salk Institute study suggests that estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue. Across the body, tiny bean-shaped structures called ...

“It was the first hormone that developed in evolution; every organ in the body has a receptor for estrogen.” Reproduction aside, estrogen plays an important role in numerous functions of the ...

Estrogen Receptor-Positive (ER+) breast cancer is the most common type of breast cancer, accounting for about 70–80% of all cases [1], [4].This form of cancer is characterized by cells that have ...

Hormone Receptor-Positive Breast Cancer. About 80% of all breast cancers are “ER-positive.” That means the cancer cells grow in response to the hormone estrogen. About 65% of these are also ...

Vepdegestrant is an oral proteolysis-targeting chimera (PROTAC) estrogen receptor (ER) degrader that directly harnesses the ubiquitin–proteasome system.In this phase 3, open-label, randomized ...

Estrogen receptor alpha (ER), progesterone receptor (PR), and androgen receptor (AR) have been implicated in the pathophysiology of other cancer types.