Huntington’s disease is a rare genetic disorder affecting movement, memory, and mood. Here’s what we know—and what’s ahead.

To date, the GeM-HD consortium has studied thousands of people with HD and hundreds of thousands of spelling changes in every ...

HD gene linked to better brain development in early life. Huntington's disease is caused by a mutation in the huntingtin (HTT) gene. The protein produced by the HTT gene is necessary for normal ...

Huntingtin was the first disease gene mapped to a specific chromosome. How did scientists do it and what have we learned since then? HD is a rare, adult-onset, autosomal dominant, progressive ...

The finding may also have implications for developing effective treatments for HD. If the gene’s early action is beneficial, then simply aiming to knock out the gene might result in loss of the ...

HD gene linked to better brain development in early life . Huntington’s disease is caused by a mutation in the huntingtin (HTT) gene. The protein produced by the HTT gene is necessary for normal ...

The Food and Drug Administration has granted Breakthrough Therapy designation to AMT-130 for the treatment of Huntington disease (HD). AMT-130 is a one-time, investigational gene therapy that is ...

The genetic mutation that causes Huntington’s disease (HD)—a devastating brain disease that disrupts mobility and diminishes cognitive ability—may also enhance early brain development and play a role ...