Axolotls are known for their ability to grow back just about any body part that is bitten off by a predator, but the trigger for this regeneration was a mystery until now. It turns out that retinoic ...

Limb formation is currently explained by a long-standing model, which states that signals from tissue in the limb bud called the apical ectodermal ridge (AER) instruct cells of the upper arm to form ...

Globally, close to 60 million people are living with limb loss. Amputations can result from various medical conditions such as tumors, infections, and birth defects, or due to trauma from industrial ...

A potentially alternative treatment for OA, a debilitating joint disease that affects more than 500 million people worldwide, is the regeneration of cartilage from stem cells. Learn more in Stem Cell ...

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or "reprogram" fibroblasts - the most commonly found cells in skin and ...

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), working in partnership with researchers at the Institut de Recherches Cliniques de Montréal (IRCM) in Canada, have ...

Atsuta and his colleagues confirmed that the fibroblasts were successfully reprogrammed into cells that can produce limb tissue. They detected three important proteins found in natural limb progenitor ...