DLS and MALS in Biochemistry, Biophysics and Structural Biology Macromolecules in solution scatter light from a culminated, monochromatic beam in all directions. The scattering ... been a while. Up to ...

The larger the particle, the slower the Brownian motion. In a DLS experiment, a laser illuminates the sample, and the scattered light is detected at a known scattering angle by a fast photon detector.