Understanding how the mTOR complexes function in controlling energy metabolism will shed light on the causal contribution of mTOR to caloric restriction and intermittent fasting, which are ...

The mTOR signaling network is a central regulator of growth, metabolism, and aging; the target of the well-known drug rapamycin; and is deregulated in common diseases, including cancer and diabetes.

As the cell's molecular control center, the mTor kinase regulates cellular metabolism, growth and division. However, in cells affected by pathological change, the regulation goes awry. Scientists ...

Phytic acid-based nanomedicine against mTOR for metabolic dysfunction-associated steatohepatitis therapy. Higher Education Press . Journal Life Metabolism ...

Given the central role of mTOR in metabolism, this research provides clues to why aging-related diseases appear or worsen in people with a high body mass index and sheds light on why calorie ...

The research focused on how CePA intervenes in the phosphorylation of mTOR through the occupying effect of phosphate groups and improves inflammatory response and lipid metabolism disorders via ...