Understanding how the mTOR complexes function in controlling energy metabolism will shed light on the causal contribution of mTOR to caloric restriction and intermittent fasting, which are ...

The mTOR signaling network is a central regulator of growth, metabolism, and aging; the target of the well-known drug rapamycin; and is deregulated in common diseases, including cancer and diabetes.

As the cell's molecular control center, the mTor kinase regulates cellular metabolism, growth and division. However, in cells affected by pathological change, the regulation goes awry. Scientists ...

The protein mTOR is a central controller of growth and metabolism. Deregulation of mTOR signaling increases the risk of developing metabolic diseases such as diabetes, obesity and cancer.

Deregulation of mTOR activity leads to diabetes, obesity, aging and cancer. mTOR regulates cell growth, survival, metabolism and immunity, and hyperactivation of mTOR promotes tumor growth and ...

Phytic acid-based nanomedicine against mTOR for metabolic dysfunction-associated steatohepatitis therapy. Higher Education Press . Journal Life Metabolism ...

Biodexa Pharma activates first clinical study site for phase 3 Serenta trial in familial adenomatous polyposis: United Kingdom Saturday, June 28, 2025, 15:00 Hrs [IST] Biodexa Pha ...

Given the central role of mTOR in metabolism, this research provides clues to why aging-related diseases appear or worsen in people with a high body mass index and sheds light on why calorie ...