The achievement represents a major step forward, potentially unlocking innovations across numerous fields that rely on ...

The most common method used to study protein structures is X-ray crystallography. With this method, solid crystals of purified protein are placed in an X-ray beam, and the pattern of deflected X ...

In addition, X-ray crystallography provides an avenue for rationale structure-based drug design by determining the structure of protein/enzyme-inhibitor complexes.

Proc Natl Acad Sci, 101:16405–10, 2004.) X-ray crystallography has long been the method of choice for obtaining atomic-resolution protein structures, but it doesn't provide the whole picture. Hydrogen ...

In 1958, British biochemist John Kendrew and colleagues published the first X-ray crystallography-generated atomic structure of a protein: that of myoglobin, a heme-binding protein found in muscle ...

Jon Mason and Miles Congreve from Heptares will describe what protein-ligand X-ray data can do for your medicinal chemistry project. How these data can be interpreted and used to influence both the ...

X-ray crystallography is a technique that uses ... Here the authors show that the E3 ligase GID4 can be harnessed for targeted protein degradation and present the crystal structure of the GID4 ...

A research team has uncovered a previously unknown type of immune signaling molecule—a novel compound combining histidine and ...

One such advancement was the invention of X-ray crystallography that let scientists peer into the spatial arrangements of atoms within a molecule. Kathleen Lonsdale got in on the ground floor of X ...

One longstanding problem has sidelined life-saving drugs, stalled next-generation batteries, and kept archaeologists from ...

Novel protein cage systems can control and visualize ... of the surrounding aromatic side chains. Through detailed X-ray ...

The BCM Macromolecular X-ray crystallography core is supported in part by an NIH Shared Instrumentation Grant Award (S10OD030246, Protein Crystallization Imager) ...