A healthy 8-year-old boy presented to our dermatology clinic with a 4-week history of worsening movement limitation and pain due to skin retraction of the right axilla. There were no constitutional ...

A 34-year-old woman (gravida 3, para 2) at 16 weeks’ gestation was found to have platelets unable to be quantified because of clumping on routine prenatal blood work, with a visual estimate of 40 ...

Key points The definition and criteria used for reporting stillbirths in Canada are idiosyncratic and dated, and directly responsible for the country’s artificially high and rising stillbirth rate ...

Pre-exposure prophylaxis (PrEP) involving daily tenofovir disoproxil fumarate/emtricitabine 300/200 mg, taken orally, is a highly effective strategy for reducing the risk of HIV acquisition in adults ...

Defined as troponin elevation exceeding the 99th percentile of reference values within 30 days of noncardiac surgery due to ischemia, the estimated incidence is 12%–24% and is higher after nonelective ...

In June 2026, 2 Canadian cities will host several FIFA World Cup soccer matches. Health care systems may have to play host too, as large numbers of visitors to these cities will increase pressure on ...

Intramuscular epinephrine rapidly reverses airway edema and shock.[1][1] Current evidence does not support use of antihistamines and corticosteroids to prevent progression of anaphylaxis or biphasic ...

Key points A 75-year-old woman presented to the emergency department with acute confusion and lethargy on the third day of ...

“Failure to cope” is a label applied to patients who cannot function at home, sometimes because of new medical problems, but often owing to unaddressed chronic medical or social issues. The underlying ...

In patients who inject insulin, the most common cause of a soft-tissue abdominal mass is lipohypertrophy; however, insulin-derived amyloidosis should be included in the differential diagnosis for ...

The prevalence rises with age, reaching 5% to 7% among patients older than 70 years.[1][1] The differential diagnosis of an adrenal mass includes adenomas (both functional and nonfunctional), ...

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