The jarring of the brain against the sides of the skull can cause shearing (tearing) of the internal lining, tissues, and blood vessels that may cause internal bleeding, bruising, or swelling of the ...

Normal and shear stresses according to time are introduced as input data to the function. By employing an optimization function, a homogenized basis matrix on the fitted graphs by a second axonal ...

The frequent involvement of deep, center-median brain structures (corpus callosum, fornix, and rostral brainstem), usually to one side of the midline, cannot be explained merely either by the ...

According to the University of Pittsburgh, the device will normalize intracranial pressure before birth and address significant risks associated with untreated fetal hydrocephalus, like seizures, ...

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Their analyses identified the PTP4A2-ROBO1 pathway which is involved in axonal guidance—a signalling axis that helps establish normal brain architecture —that can become overrun by cancer cells.

Giant axonal neuropathy is a rare, autosomal recessive, pediatric, polysymptomatic, neurodegenerative disorder caused by biallelic loss-of-function variants in GAN, the gene encoding gigaxonin. We ...

The purpose of this paper is to evaluate the hypothesis that the Apparent Diffusion Coefficient (ADC) values combined with initial clinical factors indicates the depth of shearing lesions in the brain ...

Takeaway Giant axonal neuropathy (GAN) is a progressive neurodegenerative disorder. It develops from a genetic mutation that causes your nerve cells to stop functioning.