Gabe Lander and Adrian Koh talk all things cryo-EM and its pivotal role in structural biology research in this feature.

Ribonucleic acid (RNA) molecules may be best known for their job ferrying the genetic information encoded in DNA to a cell's ...

A scientific revolution is underway as researchers push to bring atomic-level precision, once reserved for small molecule ...

A new study uncovers how fine-tuning the interactions between two distinct network-forming species within a soft gel enables programmable control over its structure and mechanical properties. The ...

Structure-based drug design is the design and optimization ... and how its shape and charge cause it to interact with its biological target, ultimately eliciting a medical effect.

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

At sufficiently high concentrations, some of the compounds called per- and poly-fluoroalkyl substances self-organize into two ...

Our current research centers on computational modeling for simulating complex multiphysics biological processes ... bio-inspired design, and basic research. Particular emphases are on passive and ...

A research team has developed an innovative membrane that mimics biological ion channels to achieve highly selective lithium ...

Learn about our Editorial Policies. While AlphaFold and the subsequent AI revolution in biology garnered a lot of attention, the foundational bricks for the strides made in protein structure and ...

Our research in the Laboratory of Structural Biology aims at understanding the structure and function of biological macromolecules and their ... proteins involved in disease is informing rational ...