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Ibuprofen (Advil, Motrin), on the other hand, works for closer to four to six hours. Acetaminophen (Tylenol) is most effective for more mild pain that is not caused by inflammation, Dr. Peperzak said.

Adults can take ibuprofen and acetaminophen together as long as they stay within the recommended dose for a 24-hour period. However, doctors may not recommend it for pregnant or nursing people.

Acetaminophen in high doses causes liver disease, and that's a big deal. Now, you can take acetaminophen for years as long as you don't go above the threshold in a day period of time.

The pain relievers acetaminophen and ibuprofen are in several over-the-counter drugs. Some people even mistake the two. But they have specific purposes and can cause problems if you’re not careful.

Apparently, there is nothing to do for it but take Extra Strength Tylenol at the recommended dose. Ibuprofen or Aleve isn’t recommended because it causes liver and kidney damage.

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However, she said acetaminophen can be dangerous if you take too much of it. Anderson said overdose can lead to liver failure over the next few days if immediate treatment is not started.