The Trp 42 residue is mostly exposed in the structure of the free enzyme 3, whereas it is shielded ... to HCMV protease (in cyan for carbon atoms), chymotrypsin (yellow), and subtilisin (green).

Thus, understanding the interplay between structure, dynamics and function of enzymes in solution is ... and stability focus mostly on barnase and chymotrypsin inhibitor 2 and are technically ...