Novel Aldosterone Synthase Inhibitor Lorundrostat Shows Promise for Uncontrolled Hypertension in CKD
A new aldosterone synthase inhibitor added to SGLT2 inhibitors reduces uncontrolled blood pressure in patients with chronic kidney disease, according to the results of a phase 2 trial.
Acetylation of lysine residues in the tail domain of histone H3 is well characterized, but lysine residues in the histone globular domain are also acetylated. Histone modifications in globular domain ...
An analysis of the Systolic Blood Pressure Intervention Trial (SPRINT) indicates that nearly all adults with chronic kidney ...
Compagnie Générale des Établissements Michelin Société en commandite par actions (ENXTPA:ML) shares have experienced ...
The improved Laser ablation significantly increases the ablation area with safety, and the long-term clinical outcomes warrant further validation through large-sample clinical trials.
The manuscript by Hensley and Yildez studies the mechanical behavior of kinesin under conditions where the z-component of the applied force is minimized. The important study shows that much of the ...
Nearly all SPRINT participants with hypertension and nondiabetic chronickidney disease stages 3–4 had a net benefit (the predicted difference between benefits and harms) that favored a systolic blood ...
News-Medical.Net on MSN
Using estimated risks and preferences to justify intensive BP control in CKD patients
An analysis of the Systolic Blood Pressure Intervention Trial (SPRINT) indicates that nearly all adults with chronic kidney ...
Facephi Reports Solid 1H25 Results, Expects Strong Acceleration in 2H25, and Provides 2025–2026 Financial Guidance Positive Free Cash Flow ...
Industrial AI is redefining sustainability, cutting emissions, saving energy, and driving resilience as the next wave of AI ...
High cardiovascular fitness offers no protection against blood vessel damage from two hours of sitting, challenging common ...
MedPage Today on MSN
Novel Injection Nearly Halved Proteinuria in IgA Nephropathy
HOUSTON -- A novel self-administered shot that inhibits two key immunoregulatory cytokines reduced proteinuria in patients with IgA nephropathy, interim findings from the phase III ORIGIN 3 trial ...
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