These are the five most-favorable PrizePicks plays for the Eagles-Packers showdown on Week 10 of Monday Night Football.

The Philadelphia Eagles offense will receive a massive boost for Monday night's clash with the Green Bay Packers.

Bowen: Smith has had six or more receptions in three of his past four games played. Here, the Eagles can scheme windows for Smith on in-breaking concepts versus the Packers' zone-heavy defense, plus he will have matchups out of the slot. Let's take the over.

The Green Bay Packers are about an hour away from kickoff their Week 10 matchup of the 2025 NFL season against the Philadelphia Eagles. This particular game was one that many fans had circled on their calendars right when the 2025 NFL schedule was released.

The Packers’ defense could be a problem, holding opposing offenses to just 286.4 yards per game (fifth in the NFL) and 20.8 points per game (eighth in the NFL). However, potentially having Brown back on the field would be a huge boost.

Neither Jaire Alexander nor A.J. Dillon will face their former team on Monday night. Both are inactive for the Eagles against the Packers.

Philadelphia Eagles wide receiver A.J. Brown made a definitive injury announcement for "Monday Night Football."

The Philadelphia Eagles have decided to not trade superstar NFL All-Pro wide receiver A.J. Brown ahead of the NFL trade deadline.

The Philadelphia Eagles ' most popular name in trade rumors is star wide receiver A.J. Brown. But with the NFL trade deadline coming on Nov. 4, it doesn't seem likely that Brown gets moved. They do have another AJ up for the taking, though: AJ Dillon. ESPN's Eagles beat writer, Tim McManus, thinks Dillon makes perfect sense to trade away.

The 2025 NFL trade deadline wasn't a deal-making frenzy, though it did come with surprises, courtesy of the New York Jets.