It is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome (ALGS) in the U.S. three months of age and older and in Europe for patients two months of age and older.

In the three aforementioned studies of epidural delivery of naloxone in combination with an opioid (fentanyl or morphine), the frequency of pruritus was decreased, with no reversal of analgesia noted.

Digestive changes: Unexplained nausea or appetite reduction. Pruritus: Itchy skin without obvious cause or rash. The presence of these symptoms alongside unusual dream patterns increases the ...

Published reports on placebo-controlled clinical trials and other studies investigating the use of pure opioid antagonists for the prevention and treatment of opioid-induced pruritus (OIP ...

Itching, or pruritus, is a common symptom in people with advanced chronic kidney disease (CKD) and those undergoing hemodialysis. You may also hear this referred to as CKD-associated pruritus or ...

A new year means a new Fierce Biotech Fundraising Tracker to record the significant amounts of venture capital being funneled into the industry. We're maintaining the criteria we used for last ...

The vagina is a flexible tube that joins the uterus to the vulva. Vaginas are usually around 3 inches long but may vary widely in color, size, and shape. The vaginal opening is the part of the ...

Patients with year-round pruritus, as well as young patients with pruritus can also undergo diet trials. With this diagnostic method, Griffin explains, the objective is to replace the patient’s ...

A person may experience itchy skin without a rash due to dry skin, bug bites, some health conditions, or as a reaction to certain medications. Treatment can depend on the cause. Depending on the ...