Dennis 4 described 2 children whose intussusception he attributed to polypoid hyperplasia of Peyer's patches in the terminal 2 cm. of ileum; both were treated by ileocecal resection, with recovery.

The clusters of gut-associated lymphoid tissues in the terminal ileum are called Peyer’s patches, which contain antigen-specific germinal centers.

Gut-associated lymphoreticular tissues, such as Peyer's patches and cecal patches, are important inductive sites for mucosal immune responses. As such, gut-associated lymphoreticular tissues may ...

A 42-year-old patient loses his insurance and access to medication. When he returns 3 years later with worsening symptoms, a colonoscopy uncovers a lesion, but the diagnosis isn't so clear.

One Peyer’s patch is around 2-5cm long and consists of around 300 aggregated lymphoid follicles. These are concentrated in the distal ileum and serve to keep bacteria from entering the bloodstream.

Dendritic cells (DC) migrate to lymph nodes on expression of C-C motif chemokine receptor 7 (CCR7) and control immune activity. Leptin, an immunomodulatory adipokine, functions via leptin ...