Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

The San Francisco 49ers officially have a significant injury problem on their hands. Running back Christian McCaffrey is out ...

SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

Given that the calf strain to 49ers running back Christian McCaffrey suddenly and unexpectedly became an Achilles tendon, too ...

The San Francisco 49ers won’t have wide receiver Deebo Samuel for a couple weeks because of a calf injury he sustained late ...

The offense looked like it misses Christian McCaffrey but the defense was surprisingly exposed. Now that Deebo Samuel is hurt ...

The start of the NFL season has been littered with injuries, and the San Francisco 49ers have not escaped the outbreak. With ...

Head coach Kyle Shanahan discussed running San Francisco's offense without RB Christian McCaffrey and WR Deebo Samuel Sr., ...

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

Deebo Samuel believes that the San Francisco 49ers can still become Super Bowl champions, despite his calf injury combined with the absence of Christian McCaffrey leaving the team ...

DL Nick Bosa, WR Brandon Aiyuk and LB Fred Warner shared the team's mindset heading into the 2024 season, discussed the ...

Just keep in mind a loss last year in Minnesota was part of the 49ers’ path to the Super Bowl: Without Deebo Samuel and ...