The expected outcome of a CLIN2 award is completion of a single interventional clinical trial. CIRM anticipates funding between 9-16 CLIN2 awards in fiscal year 2025-2026, contingent on the number of ...

The objective of the Preclinical Development Program (PDEV) is to accelerate completion of preclinical development, FDA IND clearance, and clinical trial startup for stem cell-based and genetic ...

South San Francisco, CA, April 24, 2025 — The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, has approved awarding ...

Candidato terapéutico o dispositivo Plurocart consiste en condrocitos derivados de células madre pluripotentes, sembrados en un armazón; está destinado a tratar el cartílago dañado en la articulación ...

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AB-205-301 is a Phase 3 clinical study, intended to determine if the experimental therapy AB-205 is safe and effective for US FDA approval in its use with blood stem cell transplants used to cure ...

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Chromosomal microdeletion syndromes result in severe neuropsychiatric syndromes and lack therapy. This proposal will define critical genomic regions needed to generate new tools for functional rescue.

Neuropsychiatric disorders correlate to impaired metabolism, though understudied. We will describe how metabolism impacts disorders etiology and identify new, tractable therapeutic strategies. We will ...

Damage to the oral mucosal epithelium in cancer patients undergoing chemotherapy and radiation therapy remains a significant burden, resulting in pain and reduced quality of life to such a degree that ...

研究目标：本项目将探究高可信度神经精神疾病风险蛋白的相互作用、分布和功能，并识别患者基因变异的趋同病理生物学 ...

Gene therapy achieves therapeutic benefits by delivering genetic materials, packaged within a delivery vehicle, to target cells with defective genes. This approach has shown promise in treating ...