Idiopathic normal-pressure hydrocephalus is a neurologic disorder characterized by impaired gait, balance, cognition, and ...

A 30-year-old woman with a history of bulimia presented to the emergency department after swallowing a knife. She inserted the knife into the posterior oropharynx to demonstrate to her companions t ...

Five and a half months before this evaluation, the patient was admitted to the neurology unit of this hospital with multifocal left middle cerebral artery stroke, which had manifested as weakness in ...

In the Gates Foundation’s final chapter, it is doubling down on its wager that health can engender prosperity. That proposition must now contend with the mixed macroeconomic evidence.

The painkilling, antipyretic, and antiinflammatory properties of aspirin have been known for centuries. The understanding that aspirin targets cyclooxygenase-1 (COX-1) (also known as ...

To the Editor: At the time of the publication of the first PREDIMED (Prevención con Dieta Mediterránea) trial results in 2013, 1 the relative reduction of 30% in the risk of cardiovascular events ...

In patients with refractory systemic lupus erythematosus, in vivo generation of CD19 CAR T cells by means of lipid nanoparticles led to B-cell depletion, reduced disease activity, and no major toxi ...

Michael Welsh, Jesús González, and Paul Negulescu have won the 2025 Lasker–DeBakey Clinical Medical Research Award for their roles in developing treatments for cystic fibrosis.

A 46-year-old woman with end-stage liver disease complicated by recurrent hepatic hydrothorax requiring multiple thoracenteses presented with breathlessness. Chest examination found no breath sounds ...

To the Editor: In the APPLAUSE-IgAN trial, Perkovic et al. (Feb. 6 issue) 1 found that the complement factor B inhibitor iptacopan effectively reduced proteinuria in patients with IgA nephropathy, as ...

Many AI innovations could benefit patients and clinicians. Yet medicine should heed lessons from industries in which AI adoption has resulted in reduced autonomy for workers and inferior working co ...

The placement of a central venous line is an essential technique in the treatment of many hospitalized patients. This video will demonstrate the placement of a central venous catheter in the internal ...