General Hospital ’s longest recurring actor and portrayer of matriarch Monica Quartermaine, Leslie Charleson, has died at 79. Since the show’s executive producer Frank Valentini shared the news on Sunday, fans and fellow cast members have shared their reactions to the significant loss.

Colleagues are remembering the soap opera star for her "quick wit" and presence on set. She died after a long illness.

Leslie Charleson, who played cardiologist Monica Quartermaine on "General Hospital" for five decades, has died, according to the soap opera's producer. She was 79.

Soap opera veteran Leslie Charleson, who played Monica Quartermaine on "General Hospital," has died at the age of 79.

Longtime "General Hospital" star Leslie Charleson has died at 79, the show's executive producer Frank Valentini shared in a statement.

(Gray News) – “General Hospital” announced on social media Sunday that longtime actress Leslie Charleson died. She was 79 years old. The Daytime Emmy-nominated star played Monica Quartermaine on the soap opera series for nearly 50 years.

ABC Photo Archives/Disney General Entertainment Content via Getty Images Leslie Charleson, who played Dr. Monica Quartermaine on “General Hospital” for nearly half a century, has died ...

We remember soul music legend Sam Moore. He was part of the soul music group Sam & Dave, known for their hits “Hold On, I’m Comin’,” “Soul Man,” “When something

Wally Kurth joined General Hospital in 1991 as Ned Ashton, a member of the Quartermaine family — so Ned enjoyed a close relationship with his aunt, Monica Quartermaine, played by Leslie Charleson, who passed away on January 12,

The new year brought sad news, with the deaths of celebrities happening as 2025 got underway. Peter Yarrow of the famed folk group Peter, Paul and Mary died on January 7 after a battle with cancer. The same day, Meghan Markle revealed that her beloved rescue beagle, Guy, died nearly a decade after she adopted him.

Leslie Charleson, known for her role as Monica Quartermaine on “General Hospital,” has died. She was 79. Executive producer Frank Valentini announced Charleson’s death Sunday on the show’s Instagram page.