The insulin/IGF-1 signaling axis affects cell survival and proliferation through the AKT/FOXO cascade, forming a complex network with mTOR and AMPK pathways to jointly regulate lifespan and cancer ...

BP1001-A increased the levels of phosphorylated AKT and phosphorylated FOXO-1 in myoblast and hepatoma cells in the presence of insulin These initial data confirmed that by downregulating Grb2 ...

U.S. Reps. Diana DeGette, a Colorado Democrat, and Gus Bilirakis, a Florida Republican, asked the three major insulin makers last month what steps they were taking to shore up the supply of insulin.

Data suggests that insulin resistance also increases with age, as pancreatic function declines. It is also more likely to occur in people who are less physically active or have a poor diet.

Ultra-long-acting insulin: A type of insulin that begins working six hours after you take it and stays in your system for 36 hours or longer. Similar to long-acting insulin, this type does not ...

“What we found was that nationwide, about 1.3 million Americans with diabetes rationed insulin annually, and that’s about 16.5% of all those people who use insulin,” Gaffney said.

The article, “FoxO-KLF15 pathway switches the flow of macronutrients under the control of insulin,” was published in iScience at DOI: 10.1016/j.isci.2021.103446.

For One Man, It Seems to Have Worked. A new treatment using stem cells that produce insulin has surprised experts and given them hope for the 1.5 million Americans living with the disease. 333 ...

More information: Yoshinori Takeuchi et al, FoxO-KLF15 pathway switches the flow of macronutrients under the control of insulin, iScience (2021). DOI: 10.1016/j.isci.2021.103446 ...

Human insulin is synthetically made in a lab and is able to replicate the insulin naturally found in your body. Learn more about the pros and cons of human insulin.