For the finale of our pre-NFL Draft podcasts with former pro and college scout Matt Williamson, we didn’t exactly save the best for last by waiting until Wednesday to discuss the secondary.

Confirmation that a compound inhibits the intended target (drug target validation) and the identification of undesirable secondary effects ... disruption of the primary target.

However, in patients who require lipid-lowering therapy, LDL cholesterol is the primary therapeutic target; non-HDL cholesterol is recommended as a secondary target for patients with elevated ...