Trevor Lawrence, Travis Hunter and the Jacksonville Jaguars go west to face the San Francisco 49ers in Week 4 NFL football. See updates and analysis.

The Jacksonville Jaguars lost two key linemen in the first half, offensive tackle Anton Harrison and defensive end Travon Walker.

Ashlyn Puerta made history with Sporting Club Jacksonville's first-ever hat trick in Gainbridge Super League women's soccer. Was it enough for a win?

Here are the players who won't suit up for the Jacksonville Jaguars in the team's Week 4 contest against the San Francisco 49ers.

Nelson was 17th president of The Church of Jesus Christ of Latter-day Saints from Jan. 14, 2018, until his death on Sept. 27, 2025.

How many plays on offense and defense did Jacksonville Jaguars rookie Travis Hunter play against the San Francisco 49ers?

Grading the Jacksonville Jaguars' 26-21 victory over the San Francisco 49ers on Sept. 28, at Levi's Stadium in Santa Clara, Calif.

Tropical Storm Imelda is expected to further develop into a hurricane as it parallels the east coast of Florida Monday, Sept. 29.

The Jacksonville Jaguars' defense leads the NFL with 13 turnovers through the first four games of the season. Four turnovers against the San Francisco 49ers led to 17 points for the Jaguars' offense.

Florida State couldn't score in the second overtime as the Seminoles fell to Virginia 46-38. UCF can't hang with Kansas State.

Jacob Berry's walk-off home run capped the most dramatic season in Jacksonville Jumbo Shrimp Triple-A history. Here's what happened in Las Vegas.

The Jacksonville Jaguars play the San Francisco 49ers in Week 4 of the 2025 NFL season. Who wins? See our predictions and picks, plus the game odds.