Delirium occurs in 30%–50% of adults aged 65 years or older admitted to hospital, and may be hypoactive (lethargy, reduced psychomotor functioning), hyperactive (agitation, hallucinations) or mixed.1 ...

Key points The health implications of exposures to the Alberta oil sands are underresearched, despite more than a decade of calls from Indigenous communities and researchers for further investigation.

Diagnosis of loperamide abuse requires a high index of suspicion Loperamide is not detected by routine drug screens. Typically, a patient with loperamide abuse will have a history of opioid misuse or ...

A 24-year-old man was brought by ambulance to a rural hospital after a motor vehicle collision. On physical examination, he was hemodynamically unstable with a blood pressure of 60/40 mm Hg and a ...

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Background: Consent forms have become too long and often do little to help people understand the risk elements of their participation in research, instead focusing on risk reduction for research ...

Semaglutide, liraglutide, lixisenatide, dulaglutide, and tirzepatide are the current GLP1RAs available in Canada. These are approved for the treatment of type 2 diabetes and obesity and have been used ...

Key points Dried plasma is dehydrated, powdered human plasma. Once mixed with sterile water, the reconstituted plasma delivers essential coagulation factors necessary for hemostasis and supports ...

Key points New evidence has led to a change in the way that some patients with amyotrophic lateral sclerosis (ALS) are classified and treated. Based on the findings of a landmark trial,[1][1] the drug ...

Key points More than a decade after the launch of Canada’s Strategy for Patient-Oriented Research (SPOR), patient engagement is increasingly expected across the health research ecosystem.

CMAJ May 01, 2023 195 (17) E627-E628; DOI: https://doi.org/10.1503/cmaj.1096050 ...