Background: Determining optimal timing for intensifying the frequency of physician encounters for type 2 diabetes mellitus (T2DM) requires trade-offs between timely care and clinician burden. We aimed ...

Key points On Jan. 20, 2025, the incoming United States administration froze all foreign assistance funds for 90 days, including the President’s Emergency Plan for AIDS Relief (PEPFAR) funding.[1][1] ...

A 68-year-old man presented to the gastroenterology clinic with recurrent melena over 3 months with a history of recurrent spontaneous epistaxis and a familial pattern of similar bleeding among his ...

Multiple sclerosis (MS) often begins in early adulthood, and symptoms may include fatigue, pain, and mood changes. These may not be outwardly visible but can be deeply disabling.[1][1] Clinicians ...

More than 85 000 (2.3 per 1000) people in Canada have cerebral palsy, a group of disorders resulting from a nonprogressive brain lesion early in life. Seventy-five percent of those living with ...

Key points The health implications of exposures to the Alberta oil sands are underresearched, despite more than a decade of calls from Indigenous communities and researchers for further investigation.

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Background: Consent forms have become too long and often do little to help people understand the risk elements of their participation in research, instead focusing on risk reduction for research ...

Key points Dried plasma is dehydrated, powdered human plasma. Once mixed with sterile water, the reconstituted plasma delivers essential coagulation factors necessary for hemostasis and supports ...

Key points New evidence has led to a change in the way that some patients with amyotrophic lateral sclerosis (ALS) are classified and treated. Based on the findings of a landmark trial,[1][1] the drug ...

Key points More than a decade after the launch of Canada’s Strategy for Patient-Oriented Research (SPOR), patient engagement is increasingly expected across the health research ecosystem.