Key points New evidence has led to a change in the way that some patients with amyotrophic lateral sclerosis (ALS) are classified and treated. Based on the findings of a landmark trial,[1][1] the drug ...

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Key points The health implications of exposures to the Alberta oil sands are underresearched, despite more than a decade of calls from Indigenous communities and researchers for further investigation.

Background: Consent forms have become too long and often do little to help people understand the risk elements of their participation in research, instead focusing on risk reduction for research ...

Key points Dried plasma is dehydrated, powdered human plasma. Once mixed with sterile water, the reconstituted plasma delivers essential coagulation factors necessary for hemostasis and supports ...

Key points More than a decade after the launch of Canada’s Strategy for Patient-Oriented Research (SPOR), patient engagement is increasingly expected across the health research ecosystem.

People with cannabis-induced psychosis and cannabis use disorder are at high risk of schizophrenia A population-based retrospective cohort study of 9.8 million people in Ontario, Canada, found that ...

A 57-year-old woman was admitted to hospital with a 2-month history of fever and rash that had begun on her right hand and spread across her body over the previous 10 days. She had palp–able purpura ...

Although pleural infection complicates less than 10% of pneumonia-related hospital admissions, the incidence is rising globally. [1] [1] In Ontario (1996–2015), cases increased from 2.9 to 6.7 per 100 ...

Since late 2023, new outbreaks have been reported in Bolivia, Brazil, Peru, and Cuba, including among travellers returning to Canada and the United States. [1] [1], [2] [2] Malaria, Zika, dengue, and ...

Jane S. Thornton, William N. Morley and Samir K. Sinha Physical activity is a modifiable risk factor for more than 30 chronic conditions relevant to the older adult; 150 minutes per week of moderate ...

Correctional populations are characterized by disproportionately elevated levels of chronic diseases, including substance use and mental health disorders. In contexts of the present drug overdose ...