Bronchiectasis guidelines are inconsistent with regard to the effectiveness of mucoactive agents, and their use varies ...

Idiopathic normal-pressure hydrocephalus is a neurologic disorder characterized by impaired gait, balance, cognition, and bladder control in older adults. The disorder is treated with shunt ...

In a patient with treatment-resistant ulcerative colitis, CD19 CAR T-cell therapy led to drug-free remission and mucosal healing, suggesting that B-cell targeting may offer a novel therapeutic pathway ...

The painkilling, antipyretic, and antiinflammatory properties of aspirin have been known for centuries. The understanding that aspirin targets cyclooxygenase-1 (COX-1) (also known as ...

Virtually every physician in the world has, at one time or another, read the Case Records of the Massachusetts General Hospital (the reports of the Clinicopathological Conferences [CPCs]) in the ...

Oral semaglutide at a dose of 25 mg may provide an alternative treatment option to injectable semaglutide (2.4 mg) and higher-dose oral semaglutide (50 mg) for persons with overweight or obesity. In a ...

There is an urgent need for low- and middle-income countries to ensure equitable, affordable, and sustained access to tobacco-cessation medications at scale.

In patients with refractory systemic lupus erythematosus, in vivo generation of CD19 CAR T cells by means of lipid nanoparticles led to B-cell depletion, reduced disease activity, and no major toxi ...

In the Gates Foundation’s final chapter, it is doubling down on its wager that health can engender prosperity. That proposition must now contend with the mixed macroeconomic evidence.

A previously healthy 36-year-old woman presented with a 2-day history of severe chest pain and epigastric pain associated with nausea and vomiting. The patient reported that she had consumed uncooked ...

To the Editor: At the time of the publication of the first PREDIMED (Prevención con Dieta Mediterránea) trial results in 2013, 1 the relative reduction of 30% in the risk of cardiovascular events ...

A previously healthy 44-year-old man presented with a 4-day history of an itchy rash and a 2-day history of fever and malaise. A pleomorphic eruption of papules and pustules of different sizes and ...