Interleukin 6 - Wikipedia
IL-6 is an important mediator of fever and of the acute phase response. IL-6 is responsible for stimulating acute phase protein synthesis, as well as the production of neutrophils in the bone …
IL-6 in inflammation, autoimmunity and cancer - PMC
The IL-6 amplifier (IL-6 Amp) is an amplification mechanism for the production of IL-6 and a variety of other cytokines and chemokines through a synergic interaction between STAT3 and nuclear factor …
Interleukin-6 cytokine: An overview of the immune regulation ...
Oct 1, 2022 · IL-6 dysregulation underlies inflammatory, autoimmunity, and cancer pathogenesis.
Interleukin 6: at the interface of human health and disease
Sep 28, 2023 · Interleukin 6 (IL-6) is a pleiotropic cytokine executing a diverse number of functions, ranging from its effects on acute phase reactant pathways, B and T lymphocytes, blood brain barrier …
What Is Interleukin-6? Its Role in Health and Disease
Jun 26, 2025 · Interleukin-6, or IL-6, is a protein that functions as a signaling molecule, or cytokine, that acts as a messenger between cells to coordinate various biological processes.
Interleukin-6 Signaling Pathways and Functions - Nature
In classic signalling, IL-6 binds to the membrane-bound IL-6 receptor (IL-6R) and subsequently engages the signal-transducing subunit gp130, conferring regenerative and protective effects.
IL-6 in Inflammation, Immunity, and Disease - CSHL P
IL-6 is a soluble mediator with a pleiotropic effect on inflammation, immune response, and hematopoiesis. At first, distinct functions of IL-6 were studied and given distinct names based on …